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The PoP design has desirable properties, such as\ncoherence and consistency. Moreover, the PoP design provides\nbetter empirical performance than the BOIN and Keyboard design\nwith respect to high average probabilities of choosing the MTD\nand slightly lower risk of treating patients at subtherapeutic\nor overly toxic doses.", "License": "GPL-2", "Encoding": "UTF-8", "RoxygenNote": "7.2.3", "VignetteBuilder": "knitr", "NeedsCompilation": "no", "Packaged": { "Date": "2026-05-24 08:28:16 UTC", "User": "root" }, "Author": "Chenqi Fu [aut], Xinying Fang [aut, cre], Shouhao Zhou [aut]", "Repository": "https://cran.r-universe.dev", "Date/Publication": "2024-07-01 02:48:11 UTC", "RemoteUrl": "https://github.com/cran/PoPdesign", "RemoteRef": "HEAD", "RemoteSha": "a8c04a5a4b5d334d97f027738e27af35e34ba31e", "MD5sum": "3996370e87a06b4eeb5f52647d2b79e0", "_user": "cran", "_type": "src", "_file": "PoPdesign_1.1.0.tar.gz", "_fileid": "7afecca5914dd26f5ea6f33fb8ee90b4d6536ff8df3c955ba78177a3cc1d72ca", "_filesize": 542004, "_sha256": 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1719802091 }, "_maintainer": { "name": "Xinying Fang", "email": "xf.research@outlook.com" }, "_registered": true, "_dependencies": [ { "package": "Iso", "role": "Imports" }, { "package": "knitr", "role": "Imports" }, { "package": "magick", "role": "Imports" }, { "package": "rmarkdown", "role": "Suggests" } ], "_owner": "cran", "_selfowned": false, "_usedby": 0, "_updates": [], "_tags": [], "_stars": 0, "_contributors": [ { "user": "vivid225", "count": 5, "uuid": 55261844 } ], "_userbio": { "uuid": 6899542, "type": "organization", "name": "cran", "description": "Unofficial read-only mirror of all CRAN R packages" }, "_downloads": { "count": 213, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/PoPdesign" }, "_searchresults": 4, "_rbuild": "4.6.0", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/PoPdesign.html", "extra/readme.html", "extra/readme.md", "manual.pdf" ], "_realowner": "cran", "_cranurl": false, "_releases": [ { "version": "1.0.0", "date": "2021-12-08" }, { "version": "1.0.1", "date": "2022-02-27" }, { "version": "1.0.2", "date": "2022-09-29" }, { "version": "1.0.3", "date": "2022-10-02" }, { "version": "1.0.4", "date": "2023-12-10" }, { "version": "1.1.0", "date": "2024-06-30" } ], "_exports": [ "get.boundary.pop", "get.oc.pop", "select.mtd.pop" ], "_help": [ { "page": "get.boundary.pop", "title": "Generate the dose escalation and de-escalation boundaries for single-agent trials.", "topics": [ "get.boundary.pop" ] }, { "page": "get.oc.pop", "title": "Operating characteristics for single-agent trials", "topics": [ "get.oc.pop" ] }, { "page": "plot.pop", "title": "Plot the flowchart and simulation results for PoP designs", "topics": [ "plot.pop" ] }, { "page": "print.pop", "title": "Generate descriptive summary for objects returned by other functions", "topics": [ "print.pop" ] }, { "page": "select.mtd.pop", "title": "Maximum tolerated dose (MTD) selection for single-agent trials", "topics": [ "select.mtd.pop" ] }, { "page": "summary.pop", "title": "Generate descriptive summary for objects returned by other functions in PoPdesign", "topics": [ "summary.pop" ] } ], "_readme": "https://github.com/cran/PoPdesign/raw/HEAD/README.md", "_rundeps": [ "curl", "evaluate", "highr", "Iso", "knitr", "magick", "magrittr", "Rcpp", "xfun", "yaml" ], "_vignettes": [ { "source": "vignette_for_PoP_design.Rmd", "filename": "vignette_for_PoP_design.html", "title": "PoP Design", "engine": "knitr::rmarkdown", "headings": [ "Introduction", "Methods", "Dose transition", "Dose elimination", "Theoretical properties", "Installation", "Obtaining dose escalation and de-escalation boundaries", "Set self-determined cutoffs", "Simulate operative characteristics", "Select the MTD" ], "created": "2021-12-08 07:50:14", "modified": "2024-07-01 02:48:11", "commits": 6 } ], "_score": 2.6989700043360187, "_indexed": true, "_nocasepkg": "popdesign", "_universes": [ "cran" ], 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