{ "_id": "6a141e66acfb0bcc41d3e00e", "Package": "PlatformDesign", "Title": "Optimal Two-Period Multiarm Platform Design with New\nExperimental Arms Added During the Trial", "Version": "2.1.4", "Authors@R": "c(person(\"Xiaomeng\", \"Yuan\", , \"xiaomeng.yuan@stjude.org\", role = c(\"aut\", \"cre\")),\nperson(\"Haitao\", \"Pan\", , \"Haitao.Pan@stjude.org\", role = c(\"aut\")))", "Description": "Design parameters of the optimal two-period multiarm\nplatform design (controlling for either family-wise error rate\nor pair-wise error rate) can be calculated using this package,\nallowing pre-planned deferred arms to be added during the\ntrial. More details about the design method can be found in the\npaper: Pan, H., Yuan, X. and Ye, J. (2022) \"An optimal\ntwo-period multiarm platform design with new experimental arms\nadded during the trial\". Manuscript submitted for publication.\nFor additional references: Dunnett, C. W. 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"Imports" }, { "package": "knitr", "role": "Suggests" }, { "package": "rmarkdown", "role": "Suggests" }, { "package": "ggplot2", "role": "Suggests" }, { "package": "testthat", "version": ">= 3.0.0", "role": "Suggests" } ], "_owner": "cran", "_selfowned": false, "_usedby": 0, "_updates": [], "_tags": [], "_stars": 0, "_userbio": { "uuid": 6899542, "type": "organization", "name": "cran", "description": "Unofficial read-only mirror of all CRAN R packages" }, "_downloads": { "count": 187, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/PlatformDesign" }, "_searchresults": 3, "_rbuild": "4.6.0", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/contents.json", "extra/NEWS.html", "extra/NEWS.txt", "extra/PlatformDesign.html", "manual.pdf" ], "_realowner": "cran", "_cranurl": false, "_releases": [ { "version": "1.0.1", "date": "2022-06-13" }, { "version": "2.1.3", "date": "2022-10-24" }, { "version": "2.1.4", "date": 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controlling for FWER or PWER", "topics": [ "one_stage_multiarm" ] }, { "page": "platform_design", "title": "Design an optimal two-period multiarm platform trial with new experimental arms added during the trial, controlling for FWER or PWER", "topics": [ "platform_design" ] }, { "page": "platform_design2", "title": "A faster version of platform_design()", "topics": [ "platform_design2" ] } ], "_rundeps": [ "mvtnorm" ], "_vignettes": [ { "source": "PlatformDesign.Rmd", "filename": "PlatformDesign.html", "title": "PlatformDesign", "engine": "knitr::rmarkdown", "headings": [ "Example 1: the optimal two-period multiarm trial design with delayed arms, controlling for FWER", "Step 1: initial setup", "Step 2: Correlation Matrix 1", "Step 3: Critical Value 1", "Step 4: Sample Sizes 1", "Step 5: Disjunctive Power 1", "Step 6: Timing of Adding New Arms", "Step 7: Initial Setup 2", "Step 8: Admissible Set", "Step 9: Correlation Matrix 2", "Step 10: Critical Value 2", "Step 11: Marginal Power 2", 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