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  "Title": "Optimal Two-Stage Designs for Ordered Categorical Outcomes",
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  "Description": "Functions to design and simulate optimal two-stage\nrandomized controlled trials (RCTs) with ordered categorical\noutcomes, using rank-based tests and interim decision rules for\nfutility and superiority, following Park (2025)\n<doi:10.1371/journal.pone.0318211>. The functions 'rule()',\n'op()' and 'design_table()' provide a single entry point for\nconstructing designs, evaluating their operating\ncharacteristics, and tabulating several designs at once. The\nseparate functions provided for each combination of test\nstatistic and stopping rule up to version 1.0.2 were deprecated\nin 1.0.3 and are removed here. Please see the package reference\nmanual and the vignette for details.",
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        "OptOTrials"
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        "Step 1: check the proportional odds assumption",
        "Step 2: build a design",
        "Step 3: operating characteristics",
        "Step 4: comparing criteria",
        "Degenerate optima",
        "Choosing between asymptotic and exact approaches",
        "The effect size behind a design",
        "A note on the name rule()",
        "Moving from the earlier interface"
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      "modified": "2026-09-23 06:06:58",
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