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  "Title": "Trial Design in Respiratory Disease Based on the Win Probability",
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  "Description": "Provides analysis results and trial simulation functions\nfor the I-SPY Acute Respiratory Disease Syndrome trial based on\ncomposite ranked outcomes. The composite ranked outcome is a\nhierarchical outcome where trial participants are ranked first\nby 28 day mortality, then ventilator days, then by advanced\nrespiratory support days. A Bayesian win probability approach\nis used for analysis. Trial design options include group\nsequential looks for safety, superiority, futility, and\nadjustment of randomization probabilities.",
  "License": "GPL-2",
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  "Author": "Andrew G Chapple [aut, cre], Andrew Chapple [ctb], Peter\nNorwood [ctb], Martin Eklund [ctb], Derek Russell [ctb], Phil\nBeineke [ctb], Quantum Leap Healthcare Collaborative [ctb, cph]",
  "Maintainer": "Andrew G Chapple <a.chapple@qlhc.org>",
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      "name": "CONTROL_ADVANCED_DISTRIBUTION_NO_VENT",
      "title": "Example of a non-parametric density estimate of advanced respiratory days in participants who were never ventilated used for simulation.",
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      "title": "Example of a non-parametric density estimate of advanced respiratory days in participants who were never ventilated used for simulation.",
      "topics": [
        "CONTROL_ADVANCED_DISTRIBUTION_NO_VENT"
      ]
    },
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      "title": "Example of a non-parametric density estimate of advanced respiratory days in participants who were ventilated used for simulation.",
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      "title": "Example of dataset used for the I-SPY ARDS win hierarchy",
      "topics": [
        "Example_Data"
      ]
    },
    {
      "page": "Get_ARDS_Win_Probability",
      "title": "Provides analysis results related to the I-SPY ARDS composite ranking.",
      "topics": [
        "Get_ARDS_Win_Probability"
      ]
    },
    {
      "page": "Get_True_Win_Probability",
      "title": "Gives the true win probability, mean ventilator days, and advanced respiratory days for a set of simulation parameters.",
      "topics": [
        "Get_True_Win_Probability"
      ]
    },
    {
      "page": "Sim_ARDS_Win_Probability",
      "title": "Provides operating characteristics for a group sequential design using the I-SPY ARDS hierarchical composite ranked endpoint and gating strategy with gating strategy and Bayesian Wilcoxon Rank-Sum test.",
      "topics": [
        "Sim_ARDS_Win_Probability"
      ]
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