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  "Title": "Generalized UniFrac Distances, Distance-Based Multivariate\nMethods and Feature-Based Univariate Methods for Microbiome\nData Analysis",
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      "headings": [
        "1. Introduction",
        "2. Installation",
        "3. Running ZicoSeq",
        "3.1 Loading the example data",
        "3.2 Running ZicoSeq function",
        "3.3 Some notes on using ZicoSeq",
        "3.3.1 Winsorization",
        "3.3.2 Posterior sampling",
        "3.3.3 Omnibus testing",
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        "3.4 ZicoSeq output",
        "3.4.1 p-values",
        "3.4.2 R^2 (percentage of variance explained)",
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        "3.6.2 General data types",
        "3.6.3 Random effect model - within-subject comparisons",
        "4. References",
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      "created": "2022-04-05 21:42:29",
      "modified": "2025-08-25 21:20:02",
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