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  "Author": "Dandi Qiao, Michael H. Cho",
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  "Description": "Implements the gene-based segregation test(GESE) and the\nweighted GESE test for identifying genes with causal variants\nof large effects for family-based sequencing data. The methods\nare described in Qiao, D. Lange, C., Laird, N.M., Won, S.,\nHersh, C.P., et al. (2017). <DOI:10.1002/gepi.22037>.\nGene-based segregation method for identifying rare variants for\nfamily-based sequencing studies. Genet Epidemiol 41(4):309-319.\nMore details can be found at\n<http://scholar.harvard.edu/dqiao/gese>.",
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    {
      "page": "GESE-package",
      "title": "Gene-Based Segregation Test",
      "topics": [
        "GESE-package"
      ]
    },
    {
      "page": "condSegProbF",
      "title": "Computes conditional segregation probability for the family",
      "topics": [
        "condSegProbF"
      ]
    },
    {
      "page": "database",
      "title": "database file in example",
      "topics": [
        "database"
      ]
    },
    {
      "page": "dataRaw",
      "title": "dataRaw - a data frame containing the pedigree, phenotype and genotype information",
      "topics": [
        "dataRaw"
      ]
    },
    {
      "page": "GESE",
      "title": "Gene-Based Segregation Test",
      "topics": [
        "GESE"
      ]
    },
    {
      "page": "GESE-internal",
      "title": "GESE package internal functions",
      "topics": [
        "GESE-internal functions"
      ]
    },
    {
      "page": "getSegInfo",
      "title": "Computes segregation information for different mode of inheritance.",
      "topics": [
        "getSegInfo"
      ]
    },
    {
      "page": "mapInfo",
      "title": "mafInfo - example data",
      "topics": [
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      "topics": [
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    },
    {
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      "title": "Trims the pedigree structure to include one lineage only.",
      "topics": [
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    },
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      "filename": "my-vignette.html",
      "title": "GESE package vignette",
      "author": "Dandi Qiao",
      "engine": "knitr::rmarkdown",
      "headings": [
        "3.1 Compute variant-based and gene-based segregation information for different mode of inheritance.",
        "3.2 Compute gene-based segregation test.",
        "3.3 Compute the weighted gene-based segregation test.",
        "3.4. Other useful methods",
        "3.4.1. Trimming the pedigree file",
        "3.4.2. Compute the conditional segregating probability"
      ],
      "created": "2016-08-05 17:20:55",
      "modified": "2017-05-18 17:16:22",
      "commits": 3
    }
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