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  "Title": "Objective Comparison of Phase I Dose-Finding Designs",
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  "Description": "Generate decision tables and simulate operating\ncharacteristics for phase I dose-finding designs to enable\nobjective comparison across methods. Supported designs include\nthe traditional 3+3, Bayesian Optimal Interval (BOIN) (Liu and\nYuan (2015) <doi:10.1158/1078-0432.CCR-14-1526>), modified\nToxicity Probability Interval-2 (mTPI-2) (Guo et al. (2017)\n<doi:10.1002/sim.7185>), interval 3+3 (i3+3) (Liu et al. (2020)\n<doi:10.1177/0962280220939123>), and Generalized 3+3 (G3).\nProvides visualization tools for comparing decision rules and\noperating characteristics across multiple designs\nsimultaneously.",
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  "Author": "Yuan Ji [aut], Yunxuan Zhang [aut, cre]",
  "Maintainer": "Yunxuan Zhang <yunxuanz@uchicago.edu>",
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    "design_boin",
    "design_g3plus3",
    "design_i3plus3",
    "design_mtpi2",
    "generate_decision_table",
    "generate_oc_plot",
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    "get_decision_boin",
    "get_decision_g3plus3",
    "get_decision_i3plus3",
    "get_decision_mtpi2",
    "load_true",
    "oc_plot",
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    "run_sim_boin",
    "run_sim_g3plus3",
    "run_sim_i3plus3",
    "run_sim_mtpi2",
    "run_simulation",
    "select_mtd",
    "summarize_metric"
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    {
      "page": "decision_table",
      "title": "Generate Decision Tables with S3 Support",
      "topics": [
        "decision_table"
      ]
    },
    {
      "page": "design_constructors",
      "title": "Design Constructor Functions",
      "topics": [
        "design_3plus3",
        "design_boin",
        "design_constructors",
        "design_g3plus3",
        "design_i3plus3",
        "design_mtpi2"
      ]
    },
    {
      "page": "generate_decision_table",
      "title": "Generate the decision table(s) for a single or multiple designs",
      "topics": [
        "generate_decision_table"
      ]
    },
    {
      "page": "generate_oc_plot",
      "title": "Generate the plot(s) displaying operating characteristics for a single or multiple designs",
      "topics": [
        "generate_oc_plot"
      ]
    },
    {
      "page": "get_decision",
      "title": "Generate Decision Tables for Phase I Dose-Finding Designs",
      "topics": [
        "get_decision",
        "get_decision.boin_design",
        "get_decision.default",
        "get_decision.g3plus3_design",
        "get_decision.i3plus3_design",
        "get_decision.mtpi2_design",
        "get_decision.threethree_design"
      ]
    },
    {
      "page": "get_decision_3plus3",
      "title": "Dosing decision for the 3+3 design",
      "topics": [
        "get_decision_3plus3"
      ]
    },
    {
      "page": "get_decision_boin",
      "title": "Dosing decision for the BOIN design",
      "topics": [
        "get_decision_boin"
      ]
    },
    {
      "page": "get_decision_g3plus3",
      "title": "Dosing decision for the G3 design",
      "topics": [
        "get_decision_g3plus3"
      ]
    },
    {
      "page": "get_decision_i3plus3",
      "title": "Dosing decision for the i3+3 design",
      "topics": [
        "get_decision_i3plus3"
      ]
    },
    {
      "page": "get_decision_mtpi2",
      "title": "Dosing decision for the mTPI2 design",
      "topics": [
        "get_decision_mtpi2"
      ]
    },
    {
      "page": "load_true",
      "title": "Load several commonly used scenarios",
      "topics": [
        "load_true"
      ]
    },
    {
      "page": "oc_plot",
      "title": "Generate Operating Characteristics Plots with S3 Support",
      "topics": [
        "oc_plot"
      ]
    },
    {
      "page": "run_sim_3plus3",
      "title": "Simulations for the 3+3 design.",
      "topics": [
        "run_sim_3plus3"
      ]
    },
    {
      "page": "run_sim_boin",
      "title": "Simulations for the BOIN design.",
      "topics": [
        "run_sim_boin"
      ]
    },
    {
      "page": "run_sim_g3plus3",
      "title": "Simulations for the G3 design.",
      "topics": [
        "run_sim_g3plus3"
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    },
    {
      "page": "run_sim_i3plus3",
      "title": "Simulations for the i3+3 design.",
      "topics": [
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    {
      "page": "run_sim_mtpi2",
      "title": "Simulations for the mTPI2 design.",
      "topics": [
        "run_sim_mtpi2"
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    },
    {
      "page": "run_simulation",
      "title": "Run Simulations for Phase I Dose-Finding Designs",
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        "run_simulation.boin_design",
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        "run_simulation.g3plus3_design",
        "run_simulation.i3plus3_design",
        "run_simulation.mtpi2_design",
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      "title": "Select the maximum tolerated dose (MTD) using isotonic regression",
      "topics": [
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      ]
    },
    {
      "page": "summarize_metric",
      "title": "Summarize after conducting simulations",
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      "headings": [
        "Introduction",
        "Function Dependencies",
        "Part 1: Generating Decision Tables",
        "Creating Design Objects",
        "Generating Decision Tables for Individual Designs",
        "Comparing Decision Tables Across Designs",
        "Saving Decision Table Plots",
        "Other Designs",
        "Part 2: Running Simulations",
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        "Running Simulations for Individual Designs",
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        "Saving Operating Characteristic Plots",
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