Package: SIEVEseq Title: Unified Differential Expression, Variability and Skewness Analysis for RNA-Seq Data Version: 0.0.0 Date: 2026-06-07 Authors@R: c( person("Hongxiang", "Li", email = "hxli@ynnu.edu.cn", role = c("aut", "cre")), person("Tsung Fei", "Khang", email = "tfkhang@um.edu.my", role = "aut")) Maintainer: Hongxiang Li Description: Provides a unified framework for the simultaneous testing of differential expression, variability, and skewness of genes using RNA-Seq data. The framework adopts a compositional data analysis approach for modelling RNA-Seq count data, applies the centered log-ratio transformation to obtain continuous variables, and uses the skew-normal distribution for statistical inference. Methods are described in Li and Khang (bioRxiv preprint, 2024, version 3) . Depends: R (>= 4.1) Imports: sn, stats, ggplot2 Suggests: knitr, rmarkdown, testthat (>= 3.0.0) VignetteBuilder: knitr URL: https://github.com/Divo-Lee/SIEVEseq License: GPL (>= 2) Encoding: UTF-8 LazyData: TRUE Config/roxygen2/version: 8.0.0 Config/testthat/edition: 3 NeedsCompilation: no Packaged: 2026-06-25 19:58:19 UTC; root Author: Hongxiang Li [aut, cre], Tsung Fei Khang [aut] Repository: https://cran.r-universe.dev Date/Publication: 2026-06-25 18:28:45 UTC RemoteUrl: https://github.com/cran/SIEVEseq RemoteRef: HEAD RemoteSha: c610429b4510de96c06dafb247cbf88841564a92