Package: SATS
Title: Signature Analyzer for Targeted Sequencing
Version: 1.0.10
Date: 2026-07-02
Authors@R: c(person(given="DongHyuk", family="Lee", role="aut", email="dhyuklee@pusan.ac.kr"),
             person(given="Bin", family="Zhu", role="aut", email="bin.zhu@nih.gov"),
             person(given="Bill", family="Wheeler", role="cre", email="wheelerb@imsweb.com"))
Description: SATS stands for Signature Analyzer for Targeted Sequencing
        and performs mutational signature analysis for targeted
        sequenced tumors. Unlike the canonical analysis of mutational
        signatures, SATS factorizes the mutation counts matrix into a
        panel context matrix (measuring the size of the targeted
        sequenced genome for each tumor in the unit of million base
        pairs (Mb)), a signature profile matrix, and a signature
        activity matrix. SATS also calculates the expected number of
        mutations attributed by a signature, namely signature burden,
        for each targeted sequenced tumor. For more details see Lee et
        al. (2024) <doi:10.1101/2023.05.18.23290188>.
Imports: stats, glmnet, GenomicRanges, IRanges, Biostrings, dplyr,
Depends: R (>= 4.1.0)
Suggests: testthat, BSgenome.Hsapiens.UCSC.hg19,
        BSgenome.Hsapiens.UCSC.hg38
License: GPL-2
NeedsCompilation: yes
Packaged: 2026-07-09 14:26:43 UTC; root
Author: DongHyuk Lee [aut], Bin Zhu [aut], Bill Wheeler [cre]
Maintainer: Bill Wheeler <wheelerb@imsweb.com>
Config/pak/sysreqs: zlib1g-dev
Repository: https://cran.r-universe.dev
Date/Publication: 2026-07-09 09:40:07 UTC
RemoteUrl: https://github.com/cran/SATS
RemoteRef: HEAD
RemoteSha: dbbaa08801a52899f50fad3c5b1d920629169367