Package: PlasmaMutationDetector Type: Package Title: Tumor Mutation Detection in Plasma Version: 1.7.2 Date: 2018-05-16 Author: Yves Rozenholc, Nicolas Pécuchet, Pierre Laurent-Puig Maintainer: Yves Rozenholc Description: Aims at detecting single nucleotide variation (SNV) and insertion/deletion (INDEL) in circulating tumor DNA (ctDNA), used as a surrogate marker for tumor, at each base position of an Next Generation Sequencing (NGS) analysis. Mutations are assessed by comparing the minor-allele frequency at each position to the measured PER in control samples. License: MIT + file LICENSE Imports: S4Vectors (>= 0.16.0), Rsamtools (>= 1.30.0), rtracklayer (>= 1.38.0), robustbase (>= 0.92-8), SummarizedExperiment (>= 1.8.0) Depends: R (>= 3.4.0), ggplot2 (>= 2.2.0), grid (>= 3.4.0), GenomicRanges (>= 1.30.0), VariantAnnotation (>= 1.24.0) Encoding: UTF-8 RoxygenNote: 6.0.1 LazyData: true NeedsCompilation: no Packaged: 2026-10-03 08:52:36 UTC; root Config/pak/sysreqs: libbz2-dev liblzma-dev libssl-dev xz-utils zlib1g-dev Repository: https://cran.r-universe.dev Date/Publication: 2018-06-11 06:43:09 UTC RemoteUrl: https://github.com/cran/PlasmaMutationDetector RemoteRef: HEAD RemoteSha: 9a5b641f806d9f6b66411a71205ebd1d83f4ee75