NEWS

---

PathoFMPred 0.1.0

First CRAN submission candidate.

• Fit portable cancer-specific PLS regression and PLS-LDA collections from user-supplied pathology representation and outcome tables.
• Link tables by a required patient ID, pool repeated feature rows by mean or median, and report unmatched IDs and endpoint-specific missingness.
• Apply locally fitted or separately authorized model collections to new representation features. Research reports distinguish uncalibrated binary scores from probabilities and identify limited-evidence models.
• Provide a vignette, reference manual and tests for building and using collections from TITAN, Giga-SSL, Prov-GigaPath or future representations.
• Distribute source code only. No pretrained encoders, embeddings, fitted model collections, patient-level data or research atlas registry are bundled. Optional downloads require an explicit user-supplied source and SHA-256 checksum and never run during installation or package checks.