Package: PONG2 Type: Package Title: KIR Genotype Imputation and Model Training from SNP Array Data Version: 1.0.1 Date: 2026-05-30 Description: A scalable and accurate tool for Killer-cell Immunoglobulin-like Receptor (KIR) genotype imputation directly from SNP array data using supervised machine learning models trained across five continental ancestry groups. Uses attribute bagging and an ensemble classifier method with haplotype inference for SNPs and KIR types. Models are built from global populations in the 1000 Genomes Project and validated across diverse biobank cohorts. Methods are based on Zheng et al. (2014) and Sadeeq et al. (2026) . Authors@R: c( person("Suraju A.", "Sadeeq", email = "suraju.sadeeq@cuanschutz.edu", role = c("aut", "cre")), person("Laura A.", "Leaton", role = "aut"), person("Katherine M.", "Kichula", role = "aut"), person("Paul J.", "Norman", role = "aut"), person("Xiuwen", "Zheng", role = c("ctb", "cph"), comment = "Original HIBAG C++ code adapted in src/PONG.cpp and src/LibKIR.cpp")) Maintainer: Suraju A. Sadeeq License: GPL-3 URL: https://normanlabucd.github.io/PONG2/, https://github.com/NormanLabUCD/PONG2 BugReports: https://github.com/NormanLabUCD/PONG2/issues Depends: R (>= 4.0.0) Imports: parallel, graphics, stats, utils, tools LinkingTo: Rcpp, RcppParallel Suggests: HIBAG, knitr, rmarkdown, pkgdown, testthat VignetteBuilder: knitr Encoding: UTF-8 RoxygenNote: 7.3.3 SystemRequirements: PLINK2 (>= 2.0), minimac4 (>= 4.1.6, optional) NeedsCompilation: yes Packaged: 2026-06-24 10:27:29 UTC; root Author: Suraju A. Sadeeq [aut, cre], Laura A. Leaton [aut], Katherine M. Kichula [aut], Paul J. Norman [aut], Xiuwen Zheng [ctb, cph] (Original HIBAG C++ code adapted in src/PONG.cpp and src/LibKIR.cpp) Repository: https://cran.r-universe.dev Date/Publication: 2026-06-24 08:36:40 UTC RemoteUrl: https://github.com/cran/PONG2 RemoteRef: HEAD RemoteSha: ef287ae6d12713e5f2c9ae3a6b9e31f4b30151ce