Package: OneArm2stage
Title: Phase II Single-Arm Two-Stage Designs with Time-to-Event
        Outcomes
Version: 1.2.1
Authors@R: 
    c(person("Xiaomeng", "Yuan",  email="xiaomeng.yuan@stjude.org", 
    	role = c("aut", "cre")),
      person("Haitao", "Pan",  email="haitao.pan@stjude.org", role = c("aut")),
      person("Jianrong", "Wu",  email="jiwu@salud.unm.edu", role = c("aut"))
           )
Description: Two-stage design for single-arm phase II trials with
        time-to-event endpoints (e.g., clinical trials on
        immunotherapies among cancer patients) can be calculated using
        this package. Two notable advantages of the package: 1) It
        provides flexible choices from three design methods (optimal,
        minmax, and admissible), and 2) the power of the design is more
        accurately calculated using the exact variance in the
        one-sample log-rank test. The package can be used for 1)
        planning the sample sizes and other design parameters, and 2)
        conducting the interim and final analyses for the Go/No-go
        decisions. More details about the design method can be found
        in: Wu, J, Chen L, Wei J, Weiss H, Chauhan A. (2020).
        <doi:10.1002/pst.1983>.
NeedsCompilation: no
Encoding: UTF-8
RoxygenNote: 7.2.1
Imports: survival, utils, flexsurv, IPDfromKM
Suggests: knitr, rmarkdown, testthat (>= 3.0.0)
VignetteBuilder: knitr
Config/testthat/edition: 3
License: GPL (>= 3)
Depends: R (>= 3.5.0)
Packaged: 2026-07-05 06:17:35 UTC; root
Author: Xiaomeng Yuan [aut, cre], Haitao Pan [aut], Jianrong Wu [aut]
Maintainer: Xiaomeng Yuan <xiaomeng.yuan@stjude.org>
Repository: https://cran.r-universe.dev
Date/Publication: 2023-10-10 01:30:16 UTC
RemoteUrl: https://github.com/cran/OneArm2stage
RemoteRef: HEAD
RemoteSha: 430a3c079d3df8860e1ec1cb27f89736c13897c4