Package: MedZIsc
Type: Package
Title: Statistical Framework for Co-Mediators of Zero-Inflated
        Single-Cell Data
Version: 0.0.5
Authors@R: 
    c(person("Seungjun", "Ahn", email = "seungjun.ahn@mountsinai.org",
		 role = c("cre", "aut"),
	    comment = c(ORCID = "0000-0002-4816-8924")),
    person("Zhigang", "Li", email = "zhigang.li@ufl.edu",
		 role = c("ctb")))
Description: A causal mediation framework for single-cell data that
        incorporates two key features ('MedZIsc', pronounced Magics):
        (1) zero-inflation using beta regression and (2) overdispersed
        expression counts using negative binomial regression. This
        approach also includes a screening step based on penalized and
        marginal models to handle high-dimensionality. Full
        methodological details are available in our recent preprint by
        Ahn S et al. (2025) <doi:10.48550/arXiv.2507.06113>.
License: GPL-3
Encoding: UTF-8
RoxygenNote: 7.3.2
Depends: R (>= 3.5.0)
Imports: MASS, betareg, glmnet
Suggests: knitr, rmarkdown, testthat (>= 3.0.0)
LazyData: true
Config/testthat/edition: 3
NeedsCompilation: no
Packaged: 2026-09-27 11:05:10 UTC; root
Author: Seungjun Ahn [cre, aut] (ORCID:
        <https://orcid.org/0000-0002-4816-8924>), Zhigang Li [ctb]
Maintainer: Seungjun Ahn <seungjun.ahn@mountsinai.org>
Repository: https://cran.r-universe.dev
Date/Publication: 2026-08-28 18:51:03 UTC
RemoteUrl: https://github.com/cran/MedZIsc
RemoteRef: HEAD
RemoteSha: d9148cd0d2edda8876dd6c8b0b7b9ce70a8092a4