Package: LOCOM2 Type: Package Title: A Logistic Regression Model for Testing Microbial Differential Abundance Version: 1.1 Date: 2026-10-29 Authors@R: person(given = "Yi-Juan", family = "Hu", role = c("aut", "cre"), email = "yijuanhu@bicmr.pku.edu.cn") Maintainer: Yi-Juan Hu Description: Testing differential abundance at individual taxa and in a whole microbial community. The tests are based on the log-ratio of relative abundances. The tests accommodate continuous, discrete (binary, categorical), and multivariate traits, and allow adjustment of confounders. For more details see He (2026) . This package also includes the 'com2seq' function that combines two sequencing datasets (e.g., from 16S marker-gene and shotgun sequencing) for integrative analysis of differential abundance. For more details see . License: GPL (>= 2) RoxygenNote: 7.3.2 Depends: R (>= 3.5.0) Imports: Rcpp (>= 1.0.11), stats, permute, parallel, BiocParallel, matrixStats, abind, car LinkingTo: Rcpp, RcppArmadillo Suggests: testthat, survival URL: https://github.com/yijuanhu/LOCOM2 BugReports: https://github.com/yijuanhu/LOCOM2/issues Encoding: UTF-8 LazyData: true NeedsCompilation: yes Packaged: 2026-10-29 17:12:40 UTC; root Author: Yi-Juan Hu [aut, cre] Repository: https://cran.r-universe.dev Date/Publication: 2026-10-29 16:16:04 UTC RemoteUrl: https://github.com/cran/LOCOM2 RemoteRef: HEAD RemoteSha: 74554e3fdc666a2bb65b8ae557a8c113f9f0fd49