Package: ISPYARDSWinProbabilityGSDesign
Type: Package
Title: Trial Design in Respiratory Disease Based on the Win Probability
Version: 0.1.0
Authors@R: c(person("Andrew G", "Chapple", role = c("aut","cre"),
                     email="a.chapple@qlhc.org"),
                     person("Andrew", "Chapple", role = c("ctb"),
                      email = "andrewchapple21@gmail.com"),
                      person("Peter", "Norwood", role = c("ctb"),
                      email = "p.norwood@qlhc.org"),
                      person("Martin", "Eklund", role = c("ctb"),
                      email = "martin.eklund@ki.se"),
                       person("Derek", "Russell", role = c("ctb"),
                      email = "dwrussell@uabmc.edu"),
                             person("Phil", "Beineke", role = c("ctb"),
                      email = "p.beineke@qlhc.org"),
                      person("Quantum Leap Healthcare Collaborative", role=c("ctb","cph"))
                      )
Description: Provides analysis results and trial simulation functions
        for the I-SPY Acute Respiratory Disease Syndrome trial based on
        composite ranked outcomes. The composite ranked outcome is a
        hierarchical outcome where trial participants are ranked first
        by 28 day mortality, then ventilator days, then by advanced
        respiratory support days. A Bayesian win probability approach
        is used for analysis. Trial design options include group
        sequential looks for safety, superiority, futility, and
        adjustment of randomization probabilities.
License: GPL-2
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.3.2
Imports: DFBA
NeedsCompilation: no
Packaged: 2026-07-12 07:22:18 UTC; root
Author: Andrew G Chapple [aut, cre], Andrew Chapple [ctb], Peter
        Norwood [ctb], Martin Eklund [ctb], Derek Russell [ctb], Phil
        Beineke [ctb], Quantum Leap Healthcare Collaborative [ctb, cph]
Maintainer: Andrew G Chapple <a.chapple@qlhc.org>
Depends: R (>= 3.5.0)
Repository: https://cran.r-universe.dev
Date/Publication: 2025-09-15 09:10:25 UTC
RemoteUrl: https://github.com/cran/ISPYARDSWinProbabilityGSDesign
RemoteRef: HEAD
RemoteSha: 06258e34dd7804e76ccab9f6ccb70af1efb9ae28