Package: FamEvent
Type: Package
Title: Family Age-at-Onset Data Simulation and Penetrance Estimation
Version: 3.3
Date: 2026-05-14
Authors@R: c(
    person(given = "Yun-Hee",
           family = "Choi",
           role = c("aut", "cre"),
           email = "yun-hee.choi@schulich.uwo.ca"),
    person(given = "Karen",
           family = "Kopciuk",
           role = "aut"),
    person(given = "Wenqing",
           family = "He",
           role = "aut"),
    person(given = "Laurent",
           family = "Briollais",
           role = "aut"))
Description: Simulates age-at-onset traits associated with a
        segregating major gene in family data obtained from
        population-based, clinic-based, or multi-stage designs.
        Appropriate ascertainment correction is utilized to estimate
        age-dependent penetrance functions either parametrically from
        the fitted model or nonparametrically from the data. The
        Expectation and Maximization algorithm can infer missing
        genotypes and carrier probabilities estimated from family's
        genotype and phenotype information or from fitted models. Plot
        functions include pedigrees of simulated families and predicted
        penetrance curves based on specified parameter values. For more
        information see Choi, Y.-H., Briollais, L., He, W. and Kopciuk,
        K. (2021) FamEvent: An R Package for Generating and Modeling
        Time-to-Event Data in Family Designs, Journal of Statistical
        Software 97 (7), 1-30.
License: GPL (>= 2)
Encoding: UTF-8
LazyData: true
Depends: R (>= 3.3.0), survival
Imports: MASS, stats, kinship2, truncnorm, eha, pracma, cmprsk,
        matrixcalc
NeedsCompilation: no
URL: https://CRAN.R-project.org/package=FamEvent
Packaged: 2026-07-13 06:29:22 UTC; root
Author: Yun-Hee Choi [aut, cre], Karen Kopciuk [aut], Wenqing He [aut],
        Laurent Briollais [aut]
Maintainer: Yun-Hee Choi <yun-hee.choi@schulich.uwo.ca>
Repository: https://cran.r-universe.dev
Date/Publication: 2026-05-14 23:14:09 UTC
RemoteUrl: https://github.com/cran/FamEvent
RemoteRef: HEAD
RemoteSha: 647501dfa85b3bbbcdf6f4df3781474f3f2cd429