Package: DSGEr Type: Package Title: Transcriptional Disruption Score for Gene Sets Version: 1.3.1 Authors@R: c( person(given = "Pingwei", family = "Guo", email = "1489413126@qq.com", role = c("aut", "cre")), person(given = "Huijuan", family = "Li", email = "lihuijuan@xzhmu.edu.cn", role = "aut")) Description: Computes pathway-level transcriptional disruption scores from differential expression p-values using permutation tests with Generalized Pareto Distribution (GPD) tail extrapolation and false discovery rate (FDR) correction. Reference: Guo P, Li H (2026) DSGE: Disruption Score of Gene Expression for Gene-Set Enrichment Analysis. . License: MIT + file LICENSE Encoding: UTF-8 Imports: data.table, evd, methods, POT, Rcpp LinkingTo: Rcpp Suggests: AnnotationDbi, GO.db Enhances: KEGGREST, org.Hs.eg.db, reactome.db Config/roxygen2/version: 8.0.0 RoxygenNote: 7.3.3 NeedsCompilation: yes Packaged: 2026-06-30 13:19:12 UTC; root Author: Pingwei Guo [aut, cre], Huijuan Li [aut] Maintainer: Pingwei Guo <1489413126@qq.com> Repository: https://cran.r-universe.dev Date/Publication: 2026-06-30 11:56:49 UTC RemoteUrl: https://github.com/cran/DSGEr RemoteRef: HEAD RemoteSha: b6bfdae8b578fc580ef12fff131db99520e20b9c