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# CITATION file created with {cffr} R package
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cff-version: 1.2.0
message: 'To cite package "CNVreg" in publications use:'
type: software
license: GPL-3.0-only
title: 'CNVreg: CNV-Profile Regression for Copy Number Variants Association Analysis
  with Penalized Regression'
version: '1.0'
doi: 10.32614/CRAN.package.CNVreg
abstract: Performs copy number variants association analysis with Lasso and Weighted
  Fusion penalized regression. Creates a "CNV profile curve" to represent an individual’s
  CNV events across a genomic region so to capture variations in CNV length and dosage.
  When evaluating association, the CNV profile curve is directly used as a predictor
  in the regression model, avoiding the need to predefine CNV loci. CNV profile regression
  estimates CNV effects at each genome position, making the results comparable across
  different studies. The penalization encourages sparsity in variable selection with
  a Lasso penalty and encourages effect smoothness between consecutive CNV events
  with a weighted fusion penalty, where the weight controls the level of smoothing
  between adjacent CNVs. For more details, see Si (2024) <https://doi.org/10.1101/2024.11.23.624994>.
authors:
- family-names: Si
  given-names: Yaqin
  email: ysi4@ncsu.edu
- family-names: Holloway
  given-names: Shannon T.
  email: shannon.t.holloway@gmail.com
repository: https://CRAN.R-project.org/package=CNVreg
date-released: '2025-03-10'
contact:
- family-names: Holloway
  given-names: Shannon T.
  email: shannon.t.holloway@gmail.com