# -------------------------------------------- # CITATION file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # -------------------------------------------- cff-version: 1.2.0 message: 'To cite package "BayesianMCPMod" in publications use:' type: software license: Apache-2.0 title: 'BayesianMCPMod: Simulate, Evaluate, and Analyze Dose Finding Trials with Bayesian MCPMod' version: 1.1.0 identifiers: - type: doi value: 10.32614/CRAN.package.BayesianMCPMod abstract: Bayesian MCPMod (Fleischer et al. (2022) ) is an innovative method that improves the traditional MCPMod by systematically incorporating historical data, such as previous placebo group data. This R package offers functions for simulating, analyzing, and evaluating Bayesian MCPMod trials with normally distributed endpoints. It enables the assessment of trial designs incorporating historical data across various true dose-response relationships and sample sizes. Robust mixture prior distributions, such as those derived with the Meta-Analytic-Predictive approach (Schmidli et al. (2014) ), can be specified for each dose group. Resulting mixture posterior distributions are used in the Bayesian Multiple Comparison Procedure and modeling steps. The modeling step also includes a weighted model averaging approach (Pinheiro et al. (2014) ). Estimated dose-response relationships can be bootstrapped and visualized. authors: - family-names: Wojciekowski given-names: Stephan email: stephan.wojciekowski@boehringer-ingelheim.com - family-names: Andersen given-names: Lars email: lars.andersen@boehringer-ingelheim.com - family-names: Bossert given-names: Sebastian email: sebastian.bossert@boehringer-ingelheim.com preferred-citation: type: manual title: 'BayesianMCPMod: Simulate, Evaluate, and Analyze Dose Finding Trials with Bayesian MCPMod' authors: - family-names: Wojciekowski given-names: Stephan email: stephan.wojciekowski@boehringer-ingelheim.com - family-names: Andersen given-names: Lars email: lars.andersen@boehringer-ingelheim.com - family-names: Bossert given-names: Sebastian email: sebastian.bossert@boehringer-ingelheim.com year: '2025' notes: R package version 1.1.0 url: https://CRAN.R-project.org/package=bhmbasket repository: https://CRAN.R-project.org/package=BayesianMCPMod repository-code: https://github.com/Boehringer-Ingelheim/BayesianMCPMod url: https://boehringer-ingelheim.github.io/BayesianMCPMod/ date-released: '2025-03-07' contact: - family-names: Wojciekowski given-names: Stephan email: stephan.wojciekowski@boehringer-ingelheim.com